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財經時間序列預測：使用R的計量與機器學習方法

為了解決python \r\n的問題，作者何宗武 這樣論述：

　　本書為進階的教材，需要經濟計量方法和矩陣代數的基礎。時間序列預測是統計學裡非常實用的工具，不論是分析投資組合的數據、全球總經和金融市場，以及預測景氣循環變動等等，可以用過去的數據資料，預測未來趨勢，是可以符合實際決策需要的實用能力。   　　書中並介紹機器學習方法，機器學習不是指特定估計方法，學習指的是如何在資料結構中運算，以追蹤最小預測誤差的方法獲得最佳預測(tuning)。我們應用機器學習演算法訓練歷史資料，執行特徵萃取(features extraction)，再測試預測表現。依此建立一個可預測未來的模型，作為決策之用。   　　使用R語言進行時間序列預測是本書的一大特點，R語言

是統計學中普及且容易上手的分析工具，書中針對一個個資料分析步驟進行深度解說，教給讀者進行預測與評估的最實用方法。

Genome Editing Tools and Gene Drives: A Brief Overview

為了解決python \r\n的問題，作者Mudziwapasi, Reagan,Chekera, Ringisai,Ncube, Clophas Zibusiso 這樣論述：

Reagan MudziwapasiReagan Mudziwapasi is a biotechnology researcher, lecturer and entrepreneur. He is a co-founder and Operations Director at EnviroBiotech Solutions Africa, a company that develops biotechnology-based solutions. Reagan has authored several peer-reviewed journals, is a patent holder a

nd has made several inventions and conducted several consultancies. He has contributed to various discussions on biotechnology, entrepreneurship and energy inter alia. Reagan promotes awareness on genetic engineering and its safe and responsible use. He helps marginalized communities and upcoming in

ventors protect their intellectual property. Farai Faustos MashiriFarai Faustos Mashiri has been an Agricultural Science and Biology educator since 2009 at various institutions in Zimbabwe and recently South Africa. He got his BSc in Agriculture and Natural Resources in 1999 from Africa University a

nd Post Graduate Diploma in Education from Lupane State University. After graduating, his early career engagements included technical work for private enterprises in the Agricultural sector, mainly in aquaculture and horticulture. He is currently undertaking postgraduate studies in Animal Breeding a

nd Biotechnology. His research interests are in Tilapia breeding, genome editing and gene drives. His areas of interest also span the fields of Bioinformatics, Genomics, and Data Analysis using R and Python. Irvonnie ShokoIrvonnie Shoko is a founder of Divin Chen Agribusiness Solutions where she off

ers consultancy and training services in livestock production. She joined Midlands State University in 2019 as a part-time lecturer in Animal Breeding and Physiology. Prior to that, she was a research scientist at SIRDC. During her tenure at SIRDC, she helped the company to set up a robust livestock

breeding and production project. She is a graduate of the University of Zimbabwe where she obtained a BSc in Animal Science and an MSc in Biotechnology. She is currently working towards an MSc in Animal Breeding and Biotechnology at Lupane State University. She currently lives in Harare, Zimbabwe w

ith her family. She enjoys empowering communities in agribusiness. When not working, she enjoys nature walks and swimming.Berlinda Ncube Berlinda Ncube is a cofounder of Go Science Club where she helps learners come up with science projects. She joined Zezani High School in 2018 as a chemistry teach

er. She is a graduate of the National University of Science and Technology where she obtained a BSc Hons in Applied Biology and Biochemistry and Zimbabwe Open University where she obtained a postgraduate Diploma in Education. She is currently working towards obtaining an MSc in Applied Animal Breedi

ng and Biotechnology at Lupane State University. She spends most of her time empowering the Girl Child and enjoys reading novels and surfing the net. She currently lives in Bulawayo, Zimbabwe with her family. Fortune N. JomaneFortune N. Jomane is an animal scientist who specializes in animal breedin

g and genetics. He holds a BSc in Agriculture (Animal Science), an MSc in Agriculture (Animal Science) and a Ph.D. in Agriculture specializing in Animal Breeding and Genetics. His passion is enhancing animal production through exploiting genetics. He has published several peer-reviewed papers in ani

mal breeding and genetics. He is a senior lecturer and Chairperson of the Department of Animal Science and Rangeland and Lupane State University. He is the secretary for the beef and leather value chain technical assistance project implemented by the Government of Zimbabwe through the Ministry of In

dustry and Commerce, and the Ministry of Lands, Agriculture, Fisheries, Water and Rural Resettlement. Dr. Ryman ShokoDr. Ryman Shoko is a Senior Lecturer in the Department of Biological Sciences at the Chinhoyi University of Technology. His areas of expertise include molecular biology, proteomics bi

oinformatics and computational systems biology.Ringisai ChekeraRingisai Chekera is an animal scientist who specializes in animal breeding. She holds a BSc in Agriculture (Animal Science) and an MSc in Agriculture (Animal Breeding and Biotechnology). She has a great passion for building the resilienc

e of livestock farmers through the use of various breeding strategies. She has contributed to the Resilience Knowledge Hub as a researcher in a project implemented under the ZRBF project to enhance the resilience of smallholder poultry farmers. Dr. Rutendo NyamusambaDr. Rutendo Nyamusamba’s passion

lies in development and being a voice for the seemingly voiceless. It is this passion that drives her desire for research. She uses a holistic approach in solving food system challenges. Her research and professional background are strongly rooted in Agronomy and Physiology of field crops focusing o

n Sustainable Crop Production and Weed Science. She is currently working on the integration of livestock in cropping systems for both commercial and small-scale farmers. Dr. Nyamusamba has a Ph.D. in Agronomy with a minor in Statistics; an MSc. in Plant Science from South Dakota State University, US

A and a BSc. in Agriculture with an Agribusiness specialty from Africa University in Mutare, Zimbabwe. She teaches modules in Weed Science, Plant Physiology, Crop Production, Sustainable Agriculture and Statistics. Occasionally she assists with some specific modules in Agricultural Economics such as

Econometrics.Jemethious DubeJemethious Dube has been an agricultural scientist. He holds a diploma in Agriculture from Esigodini College, a BSc in Agriculture Management, a BSc Special Honors Degree in Crop Science and a Master’s Degree in Business Administration, all from the Zimbabwe Open Univers

ity. He also holds a postgraduate diploma in education from Lupane State University. He is studying towards an MSc Crop Science (Plant Breeding) with Lupane State University. His passion for the field saw him attaining. He has vast experience working with financial institutions and non-governmental

organizations. He is very passionate about fieldwork.Moira Amanda MubaniMoira Amanda Mubani is a very talented and hardworking young scientist. She holds a BSc Honors Degree in Biotechnology and is currently in her final year completing her Master’s Degree in Applied Pharmaceutical Science. She is i

nto computational chemistry, where she developed ways of analyzing a substantial amount of data. She uses molecular modeling and bioinformatics to design novel anti-tuberculosis and anticancer drugs. Moira Amanda also works on Ethno-Pharmaceuticals projects where she is involved in cannabis research

. Moira has been working at the National Biotechnology Authority (NBA) since October 2019. She was seconded by NBA to work at the African Institute of Biomedical Science and Technology (AiBST) in 2020. At AiBST gained substantial knowledge and experience in Genomics and Bioinformatics technologies.

She also on the National Biobank project. Moira was recently seconded to work on the Biobanking project with Dr. Justen Manasa at the University of Zimbabwe innovation hub. This project is key in the establishment of the Zimbabwe Genomics Center. Moira was among the 10 people selected to participate

in a hands-on workshop training in advanced genomics technologies organized by the Biomedical Research and Training Institute. This workshop further equipped her with skills in genome sequencing, bioinformatics, big data analysis software and next-generation sequencing in relation to Covid and HIV

research. Moira lives in Harare and when she is not at work Moira devotes her time to attending church services and spending quality time with her family.Mr. Clophas Zibusiso NcubeClophas Z. Ncube is an Animal Science and Agribusiness Practitioner. He has over ten years of continuous work experience

. He started his professional career by working as a field officer under a USAID-funded project for five years in Victoria Falls and Gwanda districts. Currently, he is working as the national project coordinator of the Green Jobs project for the Food and Agriculture Organisation (FAO) of the United

Nations where his main goal is to promote rural youth employment. Prior to this, he was an Agriculture team leader for five years under a USAID-funded project where he was promoting agricultural livelihoods in Gwanda and Bulilima districts. In 2018, he was awarded the Australian awards scholarship t

o study Agribusiness concentrating on value chains. Mr. Ncube is a holder of a Master of Science Degree in Agribusiness from Africa University in Mutare, Zimbabwe, a BSc in Agricultural Science and a BSc in Agricultural Science Honors Degree in Animal Science. He is currently a student for the Maste

r of Science Degree in Animal Breeding and Biotechnology at Lupane State University. When he is not working or studying, Mr. Ncube enjoys spending time with his family in Bulawayo, Zimbabwe.　Mpumuzi Masuku Mpumuzi Masuku is a final year student at Lupane State University studying towards a Master of

Science Degree in Animal Breeding and Biotechnology. He holds a BSc Honors Degree in Agriculture (Animal Science) from the University of Zimbabwe. He is detail-oriented and values self-actualization immensely. He aims to leverage proven knowledge of research in Animal Breeding, Molecular Biotechnol

ogy and Genomics. Thandanani MoyoThandanani Moyo obtained a BSc (Hons) in Applied Biology & Biochemistry from NUST, Zimbabwe. Currently, he is studying towards an MSc in Animal Breeding and Biotechnology at Lupane State University. His research interests are molecular breeding and animal health. He

is currently working as a lab Scientist at a diagnostics laboratory.Charity ChimboCharity Chimbo is a Biology and Agriculture Science educator since 2010. She holds a BSc Honors Degree in Agriculture (UZ), Post Graduate Diploma in education (ZOU) and is studying towards an MSc in Animal Breeding and

Biotechnology with LSU. Her research interests are in genomics and bioinformatics.　

超保守元素探針設計平台

為了解決python \r\n的問題，作者萬郁岑 這樣論述：

大量的基因組數據經常被用來探索分類組的演化關係，即系統發生學，使用的方法包括全基因組定序和轉錄組。然而，研究者發現，在使用Bootstrapping或貝葉斯法（Bayesian methods）的傳統系統發生支持度分析中，一些節點具有非常高的統計值，即高支持度。但使用不同類型的基因組數據時，其演化支序結果卻是矛盾的。研究者們最近使用超保留元素（Ultra-conserved Elements, UCEs）來捕捉系統發生關係的遺傳標記。UCEs是高度保守的序列，在親緣關系很遠的類群中也會共享這些通用的遺傳標記。這些遺傳標記有助於重建許多生物的演化歷史和種群關係，從而有效解決系統發生問題。為了解

類群的演化關係，研究者常需要設計一套專屬於類群的探針進行研究，但探針的設計是非常複雜的。首先，研究人員需要一個高計算能力的Linux服務器；其次，他們需要使用Linux系統進行生物資訊學操作的技能；第三，他們需要Python程式技能。這些都使一些不具備相關計算機編程背景知識的研究人員感到困難。因此，幾乎不可能為他們感興趣的特定類群設計探針來進行基因捕獲位點。因此，本研究開發了一個使用者友善的超保守元素探針設計平台，該平台具有設計特定類群探針和合併探針的功能。該系統提供沒有計算機編程背景的研究人員也能夠輕鬆分析和設計探針。本研究使用網絡框架Bootstrap來設計網頁，並通過PHP程式語言將數據

輸入到系統的自動腳本調用Phyluce軟體進行探針設計，以獲得專屬的探針序列。目前，該系統可供多個用戶線上使用，可在平台上進行探針設計、合併探針、電腦模擬測試等分析，本研究利用已發表的鞘翅目、鱗翅目、金蛛總科和未發表的同椿科、蜜蜂屬的基因組數據，在平台上進行測試探針設計和電腦模擬測試的功能，通過使用者在平台上點選功能並輸入與過去研究一致的設計參數，其設計出的探針數量與電腦模擬測試中的捕獲率和樹型與過去研究結果是相似的，通過此平台可加速研究人員使用目標定序法(即UCEs) 研究分類組的演化關係。