Markers的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列必買單品、推薦清單和精選懶人包

Radical Realism, Autofictional Narratives and the Reinvention of the Novel

為了解決Markers的問題，作者Doloughan 這樣論述：

This monograph is concerned with what it sees as two complementary phenomena: that of contemporary writers of fiction who seem to have turned their backs on the traditional novel in favour of what might be termed a radical realism, alongside a more general movement towards and interest in auto/bi

ography and memoir in the post-truth era. By reviewing the work of four authors whose trajectory to date represents engagement with novelistic as well as auto/biographical forms, it reconsiders differences between ’fiction’ and ’non-fiction’, as they pertain to both production and reception, includi

ng issues of generic categorization, the prevalence or exclusion of specific textual markers, and readerly expectations in navigating diverse and shifting literary cultures.The Norwegian author Karl Ove Knausgaard’s Min Kamp (My Struggle) series is considered in English translation in relation to it

s cross-cultural reception; it is also placed within the context of Knausgaard’s oeuvre as a whole. Some parallels between the work of Knausgaard and that of Rachel Cusk are drawn, though in the case of the latter the focus is not so much on the memoirs but on the Outline trilogy that followed the t

rilogy of memoirs and the extent to which it represents both a departure from and a continuation of some of the concerns expressed in previous non-fictional works with a specific focus on Aftermath. Comparison of Jeanette Winterson’s semi-autobiographical debut novel, Oranges Are Not the Only Fruit,

with her memoir entitled Why Be Happy When You Could Be Normal? allows for close textual reading of scenes initially treated in novelistic form and revisited in the memoir permitting discussion of points of similarity and difference in their treatment in relation to the constraints and affordances

of genre, where these apply. Discussion of Xiaolu Guo’s memoir, Once Upon A Time in the East, focusses both on its cross-cultural reception and on the place of the memoir within the Guo corpus.In some ways all four writers are less concerned with traditional aspects of story and more concerned to de

ploy a range of forms, including narrative, to serve their interest in broader questions of truth, agency and self-understanding.

Markers進入發燒排行的影片

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Markers的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

The Vital Dead: Making Meaning, Identity, and Community Through Cemeteries

為了解決Markers的問題，作者Bell, Alison 這樣論述：

＂This book builds on recent anthropological work to explore the social and cultural dynamics of cemetery practice and its transformation over generations in Virginia’s Shenandoah Valley. Anthropologist Alison Bell finds that people are using material culture-images and epitaphs on grave markers,

as well as objects they leave on graves-to assert and maintain relationships and fight against alienation. She draws on fieldwork, interviews, archival sources, and disciplinary insights to show how cemeteries both reveal and participate in the grassroots cultural work of crafting social connections

, assessing the transcendental durability of the deceased person, and asserting particular cultural values. The book’s chapters range across cemetery types, focusing on African American burials, grave sites of institutionalized individuals, and modern community memorials＂--

NFT非同質化代幣購買意圖之研究

為了解決Markers的問題，作者陳奕達 這樣論述：

隨著第三次科技革命的日趨發展，快速的進入了數位化時代，也為生活中帶來了一些改變。尤其是交易方式、商品性質的改變尤其明顯，如光碟、書籍、圖畫等，以前都要到實體店面購買，現在大家只要動動手指就可以在網路上完成整個交易；另外，還有推出數位形式供大家選購，不在侷限於商品本身的框架。NFT是將金錢、互聯網這兩個元素融合而產生出一個新的名詞。而這個名詞在這兩年不斷地廣流傳在網路、大小媒體上面，同時也獲選為2021「年度十大代表關鍵字」的冠軍，使得眾多藝術家、運動品牌、偶像名人甚至是時尚品牌都開始默默地投入NFT市場，這也提供給消費者在NFT市場上有更多的選擇。本研究以S-O-R理論為基礎，目的為探討消費

者在對於「美學觀」、「品牌知名度」、「行銷活動」、「知覺價值」、「知覺信任」、「購買意圖」及「口碑推薦」的關係之研究，並透過問卷調查方式，統計一般消費者對於NFT購買意圖的意見，並分析消費者在受到各種外在刺激構面後，個體心理的變化以及對購買意圖之關聯。研究問卷共計回收400份問卷，有效問卷數為365份，有效問卷回收率為91.3%。研究結果發現：消費者受到NFT的「外部刺激」因素後，對「自我知覺」有正向顯著的影響、消費者的「自我知覺」對於NFT「購買意圖」有正向顯著的影響、消費者的「自我知覺」對於NFT「口碑推薦」有正向顯著的影響、消費者的「自我知覺」對於「外部刺激」與「購買意圖」有起到中介的效

果。